Parkin-mediated ubiquitination regulates phospholipase C-γ1
نویسندگان
چکیده
منابع مشابه
Parkin-mediated ubiquitination regulates phospholipase C-γ1
Mutations in parkin cause autosomal recessive forms of Parkinson's disease (PD), with an early age of onset and similar pathological phenotype to the idiopathic disease. Parkin has been identified as an E3 ubiquitin ligase that mediates different types of ubiquitination, which has made the search for substrates an intriguing possibility to identify pathological mechanisms linked to PD. In this ...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2008
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2008.00443.x